Although many people take isolated nutrients as antioxidant supplements, they may not be getting the benefits they hope for. While isolated nutrients have powerful antioxidant abilities in vitro, they rarely have significant antioxidant benefits in vivo.

Adrenalin is an outstanding example of a synthetic product that is being commercialized in disregard of the difference in physiological action. The natural adrenalin is fifteen times as 35 active as the synthetic dextro form in its effect on blood vessels.