Product #458

Intracellular Defenseā„¢

( Previously known as Intracellular Coughā„¢ )

Intracellular Defenseā„¢ is a 100% FoodĀ supplement that is intended to supply nutrients, glandulars, and herbs needed to maintain and support optimal immune system health.Ā  This is a pluriglandular formula that also includes immune system supporting herbs.

90 Capsules   •   $42.00

Gluten-Free

Halal and
Biblically Kosher Compliant.

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Product Details

Coughs can have many causes, and herbs have long been used by people who have coughs [1].Ā 

Intracellular Defenseā„¢ has been formulated to provide nutritional support for those who have a pattern consistent with an intracellular bacterial infection—and who normally demonstrate this with a chronic cough which is not known to have another cause.Ā Ā 

While allergies can cause many to have chronic coughs, Intracellular Coughā„¢ is not intended to be used for coughs due to allergies. However, human research has shown that those with allergies can develop a bacterial sinusitis that contains intracellular bacteria in the sinuses [2]—for those people Intracellular Coughā„¢ may possibly be indicated.

Mainstream research involving horses and dogs confirm that some chronic coughs seem to be related to intracellular bacterial infections [3-4]. Human research has also confirmed the presence of certain chronic coughs with intracellular bacteria [2,5-8].

Some strains can include Rhodococcus equi [5], Bordetella pertussis [6] (though it tends to more acute than chronic [7]), and Bordetella bronchiseptica [7], and Anaplasma phagocytophilum [8] . ā€œThe bacteria causing diphtheria, whooping cough, cholera and other diseases secrete mono-ADP-ribosylating toxins that modify intracellular proteins ā€ [9]. Some intracellular infectious agents, such as Simkania negevensis do not seem to directly cause chronic coughs [10], even though they have been suspected as causative agents.

Because of the nature of some of these infections, normal immune support products often do not provide the type of relief that the sufferer is hoping for. Many of these infections agents are difficult to deal with [6-7], which is part of why various standard interventions are inadequate. For some in that category, Intracellular Coughā„¢ may be indicated.

Sometime in the last decade of 20 th century, some natural health professionals began specifically advising the combination of substances such as bovine glandulars, bromelain, vitamin C, B vitamins, and lecithin as nutritional support for the immune system support when intracellular bacterial infections were encountered [11]. And now for the first time, this type of relatively new strategy is now available in a 100% Food product for in the 21 st century.

Other ingredients:Ā Vegetarian (HPMC) Capsule.
Suggested use:Ā Serving size or as recommended by your health care professional. Adjust usage according to nutritional lifestyle requirements.

References

[1] Gruenwald J, Brendler T, Jaenicke C, eds. PDR for Herbal Medicine, 3 rd ed. Thompson PDR, Montvale (NJ), 2004
[2] Shapiro GG. The role of nasal airway obstruction in sinus disease and facial development. J Allergy Clin Immunol. 1988 Nov;82(5 Pt 2):935-940
[3] Christley RM, Hodgson DR, Rose RJ, Hodgson JL, Wood JL, Reid SW . Coughing in thoroughbred racehorses: risk factors and tracheal endoscopic and cytological findings. Vet Rec. 2001;148(4):99-104
[4] Peeters DE, McKiernan BC, Weisiger RM, Schaeffer DJ, Clercx C . Quantitative bacterial cultures and cytological examination of bronchoalveolar lavage specimens in dogs. J Vet Intern Med. 2000;14(5):534-541
[5] Rabagliati R, Morales A, Baudrand R, Jorquera J, Oddo D, Garcia P, Carmona MC, Cisternas M, Huete A. [Necrotizing pneumonia due to Rhodococcus equi in non HIV immunocompromised host. Case report and review]. Rev Chilena Infectol. 2005;22(2):155-60
[6] Mills KH. Immunity to Bordetella pertussis. Microbes Infect. 2001;3(8):655-77
[7] Coote JG. Environmental sensing mechanisms in Bordetella. Adv Microb Physiol. 2001;44:141-81
[8] Remy V, Hansmann Y, De Martino S, Christmann D, Brouqui P. Human anaplasmosis presenting as atypical pneumonitis in France. Clin Infect Dis. 2003;37(6):846-8
[9] Jorgensen R, Merrill AR, Yates SP, Marquez VE, Schwan AL, Boesen T, Andersen GR. Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry. Nature. 2005;436(7053):979-84
[10] Johnsen S, Birkebaek N, Andersen PL, Emil C, Jensen JS, Ostergaard L. Indirect immunofluorescence and real time PCR for detection of Simkania negevensis infection in Danish adults with persistent cough and in healthy controls. Scand J Infect Dis. 2005;37(4):251-5
[11] Thiel R. Serious Nutrition for Healthcare Professionals. Center for Natural Health Research, Arroyo Grande (CA), 1996

No Synthetic Nutrients • No Dairy • No Preservatives

* This is a nutritional product and not a medication intended to prevent, treat, or cure any illness. None of these statements has been approved by the US FDA or similar agencies. Not all citations meet peer-reviewed status so the statements are not conclusive. Professionals can, and do, disagree, regarding efficacy of ingredients in nutritional formulas.

Disclaimer: Some of these studies (or citations) may not confom to peer review standards. Therefore, the results are not conclusive. Profressionals can, and often do, come to different conclusions when reviewing scientific data. None of these statements have been reviewed by the FDA.

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